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Home / Erectile Dysfunction / Tadalafil

Tadalafil Tablets (Generic Cialis)

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What is Tadalafil?

Tadalafil, also sold under the brand name Cialis, is a medication used by many men worldwide to treat erectile dysfunction.

When taken 30-60 minutes before sexual activity, this drug increases blood flow to the penis, making it easier for men to get and maintain an erection.

The European Medicines Agency (EMA) approved Cialis in November 2002. Since then, generic versions have become available, and it has become one of the most widely used and affordable erectile dysfunction treatments.

At euroClinix, we prescribe 5 mg, 10 mg, or 20 mg Tadalafil tablets specifically to treat erectile dysfunction.

Is Tadalafil the same as Cialis?

Cialis is just the branded version of generic Tadalafil. The active ingredient, mechanism of action, effectiveness, and intended use are all the same.

The main difference between Tadalafil and Cialis is the price, as the generic version is far cheaper.

When deciding on treatment, choose whichever one you feel is more suited to your needs.

How does Tadalafil work?

The active ingredient, tadalafil, works by increasing blood flow to the penis when you get sexually excited.

It belongs to a class of medicines called PDE5 inhibitors. These medicines block an enzyme in the body responsible for erection problems. Through this mechanism of action, blood flow to the penis is increased, and the muscles are relaxed, allowing men to get and maintain an erection.

Contrary to popular belief, this drug only works when the person taking it is sexually stimulated. This means you will only get an erection if you are engaging in some form of sexual activity.

Tadalafil timeline

30-60 minutes

Initial Phase

Tadalafil begins to take effect. Monitor how you feel during this time

1-2 hours

Peak effectiveness

The effects are most strongly felt

Up to 36 hours

Total duration

The effects are felt for this time before gradually wearing off

Please note: individual experiences may vary. Always follow your healthcare provider’s instructions.

What are the benefits of Tadalafil?

Taking this medication for your erectile dysfunction offers many benefits:

Key benefits of Tadalafil

Effective for longer

The effects of Tadalafil can be experienced for up to 36 hours after taking it, earning it the nickname "the weekend pill

Fast onset of action

This medicine begins working within 30-60 minutes, giving you the freedom to take it on short notice.

High success rate

Tadalafil boasts a high success rate in men who take the medicine to treat their erectile dysfunction, as shown in clinical studies

Convenient dosing

Tadalafil is taken as needed, meaning your dosing schedule is not too time-consuming or difficult to maintain.

How effective is Tadalafil?

Tadalafil is a proven and effective treatment for erectile dysfunction, as shown in clinical studies.

In one clinical trial involving 348 men with erectile dysfunction, participants were divided into two groups: one received 20 mg of Tadalafil, while the other received a placebo.

Here are the key findings:

  • Those taking Tadalafil were more than twice as likely to engage in sexual activity successfully - on average, 59.2% of their attempts were successful, compared to only 28.3% in the placebo group.
  • Rate of successful intercourse attempts 24 hours after treatment was significantly greater - 52.9% success rate for Tadalafil compared to 29.1% for placebo.

Efficacy of Tadalafil

Tadalafil study results

Percentage of successful sexual intercourse attempts

Tadalafil

59% of men

Placebo

28% of men

Percentage of successful sexual intercourse attempts 24 hours after treatment

Tadalafil

53% of men

Placebo

29% of men

Study duration: 4 weeks

Participants: 348 men

Tadalafil vs Sildenafil: which is more effective?

Research has shown that, although both treatments are similarly effective for erectile dysfunction, Tadalafil significantly improved psychological outcomes compared to Sildenafil. In other words, patients, on average, tend to prefer Tadalafil.

There are some other differences that may make Tadalafil the preferred treatment:

  • Lasts longer - the effects last for up to 36 hours, whereas Sildenafil lasts for 4-6 hours.
  • Lower dose required - this reduces the risk of side effects.

Who can and cannot take Tadalafil?

This medication may not be suitable for everyone. When you complete a consultation, our UK-registered doctors will be able to determine if it is safe for you.

Who can take it?

This medication is suitable for men over 18 experiencing erectile dysfunction.

Who cannot take it?

Do not take Tadalafil if you:

  • Are allergic to any ingredient found in this medicine
  • Have serious heart disease
  • Had a heart attack within the last 90 days
  • Had a stroke within the last 6 months
  • Have low blood pressure or uncontrolled high blood pressure
  • Ever had loss of vision due to stroke of the eye (non-arteritic anterior ischaemic optic neuropathy)

Cautions

While not necessarily contraindications, some conditions mean the safety of this medicine will need to be determined during your consultation. Tell our medical team if you have:

  • Sickle cell anaemia (an abnormality of red blood cells)
  • Multiple melanoma (cancer of the bone marrow)
  • Leukemia (cancer of the blood cells)
  • Any deformation of your penis
  • A serious liver problem
  • A severe kidney problem
  • Had pelvic surgery
  • A removal of all or part of the prostate gland

Please disclose your health status during your online consultation with euroClinix. One of our doctors will evaluate whether Tadalafil is suitable for you and may adjust your medications if needed.

How do I take Tadalafil?

To use this medicine correctly, follow the dosage and treatment course our medical team prescribes. This ensures the drug's effectiveness and helps avoid side effects.

For best results, take your tablets:

  • With a glass of water
  • On an empty stomach

Dosage

Four dosages of erectile dysfunction tablets are available: 2.5 mg, 5 mg, 10 mg, and 20 mg.

The recommended starting dose is one 10 mg tablet before sexual activity, but your doctor may prescribe you more or less depending on your individual circumstances.

Tadalafil Dosages
Dosage When to use Consideration
2.5 mg* Daily as a continuous treatment Lower dosage to be used if you have underlying conditions
5 mg Daily as a continuous treatment Average dose for daily treatment
10 mg As needed (30-60 minutes before sexual activity), not for daily use Recommended starting dose for as-needed treatment
20 mg As needed (30-60 minutes before sexual activity), not for daily use Higher dose if 10 mg is ineffective

*At euroClinix, we do not currently stock the 2.5 mg dosage. Consult our medical team to explore all of your treatment options.

When do I take it?

You should take your tablet 30-60 minutes before sexual activity.

You do not need to take it if you are not trying to have sex, and you should not use it more than once a day. The maximum dose of Tadalafil in 24 hours is 1 pill, whatever the dosage prescribed.

How long does Tadalafil take to work?

The medicine should take effect within 30-60 minutes.

The effects can last for up to 36 hours, but peak results are usually seen 1-2 hours after you take your tablet.

What lifestyle changes should I make while taking Tadalafil?

Making some changes to your lifestyle can help treat your condition as effectively as possible. Consider implementing the following.

Lifestyle guide for Tadalafil users

Maintain a healthy weight

Being overweight or obese can increase the risk of cardiovascular problems, which can impact your ability to get and maintain an erection.

Stop smoking

Smoking can damage blood vessels, making you around twice as likely to experience erectile dysfunction.

Moderate alcohol consumption

Alcohol affects the nervous system, which can make it harder to get and maintain an erection. Try to limit your alcohol intake for better sexual performance.

Maintain regular exercise

Regular physical activity improves cardiovascular health, boosts circulation, and can make your treatment more effective. Aim for 150 minutes of moderate exercise per week if you are able.

Manage stress

Stress can lower testosterone, which can affect your sex drive and ability to maintain an erection. Practice stress-reducing techniques like meditation, yoga, and deep breathing if you feel overly stressed.

Always consult with your healthcare provider before making significant lifestyle changes.

What are Tadalafil’s side effects?

This medicine may produce side effects. These are usually mild and should go away in a few days.

If you experience any of the following side effects, stop using the medicine and seek immediate medical help.

  • Allergic reactions - symptoms include difficulty breathing, a skin rash, fever, or a swelling of the face or throat.
  • Chest pain - do not use nitrates as they can drop blood pressure dangerously low.
  • A prolonged and possibly painful erection - contact a doctor if an erection lasts for longer than 4 hours.
  • Sudden loss of vision - seek immediate medical help, as this could become permanent if not treated.

Aside from these serious side effects, there are some more to look out for.

Common side effects (may affect up to 1 in 10 people)
  • Headache
  • Back pain
  • Muscle aches
  • Pain in arms and legs
  • Facial flushing
  • Nasal congestion
  • Indigestion
Uncommon side effects (may affect up to 1 in 100 people)
  • Dizziness
  • Stomach ache
  • Feeling or being sick
  • Blurred vision
  • Eye pain
  • Difficulty breathing
  • Blood in urine
  • Prolonged erection
  • Pounding heartbeat
  • Fast heart rate
  • High or low blood pressure
  • Nose bleeds
  • Ringing in the ears
  • Swelling of the hands, feet or ankles
  • Tiredness
Rare side effects (may affect up to 1 in 1,000 people)
  • Fainting
  • Seizures
  • Swelling of the eyelids
  • Red eyes
  • Hearing loss
  • Skin changes
  • Bleeding of the penis
  • Increased sweating

How to manage side effects

Most mild side effects can be managed with these simple steps:

  • Stay hydrated
  • Take your tablet with food
  • Sit of lie down if you feel dizzy or lightheaded

To manage common side effects like headaches or flushing, stay hydrated and avoid excessive quantities of alcohol. If your symptoms are persistent or severe, consult your doctor for professional help

Dr. Caroline Fontana Lead Prescribing Doctor

For more detailed information, please refer to the patient information leaflet.

What interacts with Tadalafil?

Some medicines may interfere with the effectiveness of Tadalafil or increase the risk of side effects. Tell your doctor about any medication you take, including the following:

Can increase Tadalafil levels

  • Antifungals (e.g., Ketoconazole, Itraconazole)
  • Antibiotics (e.g., Erythromycin, Clarithromycin)
  • HIV medications (e.g., Ritonavir)
  • Grapefruit or grapefruit juice

Can lower Tadalafil levels

  • Drugs that speed up drug breakdown (e.g., Rifampicin, Phenytoin, Carbamazepine)

Can significantly lower blood pressure

  • Blood pressure medications (e.g., nitrates, Doxazosin)
  • Pulmonary hypertension medications (e.g., Riociguat)

This list does not cover all possible interactions. For a comprehensive list, please visit the interactions checker on the BNF website.

What safety advice should be followed when taking Tadalafil?

Category Status Advice
Alcohol Caution Alcohol can temporarily impair your ability to get and maintain an erection. Limit your alcohol intake before sexual activity.
Lactose intolerance Consult your doctor This medicine contains lactose. Consult your doctor before use if you have been told you are lactose intolerant.
Driving Caution This medicine can cause dizziness and affect your vision. You should be aware of how you react to this drug before driving or operating machinery.
Hydration Important Proper hydration can positively affect blood circulation, possibly improving the drug’s effectiveness and reducing the risk of side effects.

How should I store Tadalafil?

This medication does not require any special storage instructions. To safely store your tablets, follow these general guidelines:

  • Do not use this medicine after the expiry date
  • Keep this medicine out of the sight and reach of children
  • Do not throw away medicines via wastewater or household waste.*

*Take any unused medication to your local pharmacy for proper disposal. These measures help to protect the environment.

Can I buy Tadalafil without a prescription?

No, Tadalafil can only be obtained with a prescription from a licensed healthcare provider.

Prescriptions are necessary because they:

  • Ensure appropriate use for your specific condition.
  • Prevent potential misuse and associated health risks.
  • Allow for monitoring of side effects and interactions with other medications.

Viagra Connect is an over-the-counter alternative to Tadalafil. However, it is only available as 50 mg tablets.

How do I buy Tadalafil online from euroClinix?

Ordering Tadalafil online from euroClinix is convenient.

Follow these simple steps:

  1. Complete a quick online consultation to check your eligibility.
  2. UK-registered doctors review your responses to ensure the medication is right for you.
  3. Upon approval, an e-prescription will be issued.
  4. Enjoy free delivery from our licensed pharmacy with tracking details.

Your privacy is our top priority. euroClinix uses secure, encrypted transactions and complies with UK medical standards to keep your information confidential.

Start your online consultation today to enjoy professional care from the comfort of your home.

Why should I choose euroClinix?

euroClinix is trusted by thousands of users in the UK for its safe and convenient service. Here’s why:

  • Experienced doctors manage your consultations and prescriptions.
  • Online consultations, swift approvals, and discreet doorstep delivery make ordering quick and convenient.
  • A supportive team is on hand to answer treatment-related questions or concerns.
  • Patients can manage their prescriptions hassle-free through our secure platform.

Join thousands who trust euroClinix for their healthcare needs and take control of your health today.

How much does Tadalafil cost?

The price of Tadalafil at euroClinix includes everything you need:

  • Free online consultation with our experienced doctors
  • Free prescription, if approved
  • Free delivery straight to your door

Our pricing is transparent, with no hidden fees. Order today and benefit from our complete, all-inclusive service.

What alternatives are available?

If this treatment is not right for you, there are other erectile dysfunction tablets available to treat your condition.

Comparison of ED Treatments and their characteristics
Choose what to compare:
Medication Highlights Work in Lasts for Pricing When to use Dosage Sucess rate Best for
Tadalafil Same as Cialis, lower price 30-60 minutes Up to 36 hours - 30-60 minutes before sex 10 mg Up to 64% effective Long-lasting treatment at a low price
Viagra Most well-known and studied 30-60 minutes Up to 4 hours - 1 hour before sex 50 mg Up to 84% effective A trustworthy and popular treatment
Cialis Longest-lasting effects, the “weekend pill” 30-60 minutes Up to 36 hours - 30-60 minutes before sex 10 mg Up to 64% effective Long-lasting treatment
Sildenafil Same as Viagra, lower price 30-60 minutes Up to 4 hours - 1 hour before sex 50 mg Up to 84% effective. Reliable treatment at a lower price
Cialis Daily Taken daily, ongoing effects 3-5 days of daily use Continuous - At the same time each day 5 mg Up to 96% effective Daily dosing and ongoing effects
Vardenafil Highly tolerable for most people 30-60 minutes Up to 5 hours - 25-60 minutes before sex 10 mg Up to 80% effective Those not suited to other treatments
Spedra Fastest-acting 15-30 minutes Up to 5 hours - 15-30 minutes before sex 100 mg Up to 85% effective Fast-acting treatment
ED trial pack Includes Sildenafil, Tadalafil, and Vardenafil Varies per medication Varies per medication - Varies Varies Efficacy varies Exploring multiple treatment options

Tadalafil FAQs

Does Tadalafil lower blood pressure?
Is Tadalafil safe?
Does Tadalafil increase testosterone?
How long does Tadalafil stay in your system?
Is Tadalafil stronger than Viagra?
Can you stop taking Tadalafil suddenly?
Does Tadalafil increase penis size?
Can women take Tadalafil?
Is Tadalafil used for benign prostatic hyperplasia (enlarged prostate)?
Are there any discounts for being a new user?
Is it safe to order online?
Will my order be confidential?
What are the delivery options available?

Note: You must complete a short online consultation so that our doctor can ensure that the treatment is suitable for you. The above pricing should only be used as a reference. The final decision to issue this treatment lies with the prescribing doctor.

Medically reviewed by Dr. Caroline Fontana Written by our editorial team Last reviewed 24-01-2025
Tadalafil information
Type of medicinePDE5 Inhibitor
Used forTreatment of erectile dysfunction
Active ingredient(s)Tadalafil
Works byTemporarily increasing blood flow to the penis when you are sexually aroused
Effective within30-60 minutes
Available asTablets
Available dosage(s)5 mg, 10 mg, 20 mg
Usage instructionsTake one tablet 30-60 minutes before sexual activity
Packaging5 mg - blister packs containing 28 tablets
10 mg & 20 mg - blister packs containing 4 tablets
ManufacturerVarious
Branded available?Yes (Cialis available as branded)
StorageKeep at room temperature in the original packaging. Protect from moisture and direct heat.
Prescription required?Yes, get it with our FREE online consultation
Who is suitable for an online consultation*Men over 18 with erectile dysfunction

*Note: Our medical team must review your online consultation before approving this treatment. They will determine if the requested treatment and quantity are safe, appropriate, and effective for you.

Tadalafil reviews
Package of Tadalafil 2.5mg oral film-coated 28 tablets Excellent 4.5 469 patients have reviewed Tadalafil on Trustpilot
27 Nov

Works for me

Fred Macey
21 Mar

Effective product

Fred Macey
24 Feb

Effective, even for me, seems to last a while too.

Fred Macey

Further reading

Viagra and how it reacts with other medicines

Viagra and how it reacts with other medicines

Reviewed by Dr. Caroline Fontana
Viagra: the side effects explained

Viagra: the side effects explained

Reviewed by Dr. Caroline Fontana
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